Molecular Allergology User’s Guide

Molecular allergology is a further, excellent example of how allergy is linked to precision medicine and drives precision health forward.

Allergic diseases are still steadily rising and affecting a large number of individuals who are also facing an overall worsening of their clinical manifestations at any point during their life-time. Many children suffer from severe food allergy and anaphylaxis, many adolescents and young adults are under performing due to asthma and allergic rhinitis and many adults are missing work due to co-morbidities of allergic diseases. Allergy is currently a public health issue although hugely underestimated and under recognized.

There is a need to improve the care of allergic patients through better education of health professionals and the public. As part of its Mission the European Academy of Allergy and Clinical Immunology (EAACI) has started a project aimed to translate best knowledge into best practice. Atlases and Guidelines represent a comprehensive set of documents that are distributed for improving appraisal and proper management of allergy.

This User’s Guide for Molecular Allergology represents a breakthrough in improving the appraisal and management of Allergy.

Recombinant technology in the field of allergology has brought tremendous advances in allergen characterization as well as in the knowledge of immune mechanisms involved in allergic diseases. Molecular allergology takes diagnostics one-step further. It can enable you to get better perspectives on the risk connected with sensitization. Sensitization to the components is measured individually helping to pinpoint on an exact molecular level which component the patient is sensitized to. In light of this, allergen extracts are being step-by-step replaced by molecule-based products. The new developments will allow clinicians to obtain detailed information on sensitization patterns and more accurate interpretation of allergic symptoms. This information provides the basis for a refined, earlier, diagnosis of the allergic reactions and ultimately for a tailored individualized management of the patient, including opportunities for prevention.

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