Streck Immunology & Flow Cytometry Controls

In 1991, Streck used the technology it had developed for stabilizing white blood cells to develop a control for immunophenotyping by flow cytometry. The first control, CD-Chex, offered only white blood cells. These cells were stabilized in a way that the antigen sites were preserved and not destroyed by the fixative.  In 1995, Streck introduced an improved version of the control that included red blood cells. The control, CD-Chex Plus, closely resembled a patient sample as it was tested by flow cytometry. As immunophenotyping by flow cytometry moved from the research laboratory to the clinical laboratory, the need for controls grew.  CD-Chex CD34 is Streck’s whole blood control for enumerating CD34 positive cells by flow cytometry. This control offers a high level of CD34 intended for laboratories analyzing samples with greater than 0.5% CD34 positive cells. Laboratories can now more accurately assess mobilized patient samples for stem cell transplantation, including peripheral blood, apheresis products, and bone marrow.